| Product Name | Anti-Cadherin 16 Antibody [rCDH16/1071] - BSA and Azide free |
|---|---|
| Description | Recombinant mouse monoclonal [rCDH16/1071] antibody to Cadherin 16. |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | rCDH16/1071 |
| Conjugate | Unconjugated |
| Immunogen | Recombinant full-length human CDH16 protein. |
| Isotype | IgG1 |
| Molecular Weight | 130 kDa |
| Target | Cadherin 16 |
| Specificity | This antibody recognizes a protein of 130kDa, identified as Ksp-cadherin. Cadherins form a superfamily of related glycoproteins that mediate calcium-dependent cell adhesion and transmit signals from the extracellular matrix to the cytoplasm. Cadherins have been implicated in embryogenesis, tissue morphogenesis, tissue structure maintenance, cell polarization, neoplastic invasiveness and metastasis, and membrane transport. It is suggested that Ksp-cadherin is a marker for terminal differentiation of the basolateral membranes of renal tubular epithelial cells. Within the kidney, Ksp-Cadherin is found exclusively in the basolateral membrane of renal tubular epithelial cells and collecting duct cells, and not in glomeruli, renal interstitial cells, or blood vessels.Ksp-Cadherin has been suggested to distinguish Chromophobe Renal-Cell Carcinoma from Oncocytoma. |
| Reactivity | Canine, Human, Mouse, Rabbit, Rat |
| Applications | FC, IHC-P, WB |
| Working Dilutions | Flow Cytometry: 1-2 µg/million cells, WB: 1-2 µg/ml, IHC-P: 1-2 µg/ml |
| Form | Liquid |
| Diluent Buffer | Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free. |
| Concentration | 1 mg/ml |
| Storage | Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. |
| Supplier | Antibodies.com |
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