| Product Name | Anti-Calbindin Antibody [CALB1/2364] |
|---|---|
| Description | Mouse monoclonal [CALB1/2364] antibody to Calbindin. |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | CALB1/2364 |
| Conjugate | Unconjugated |
| Immunogen | Recombinant fragment, around amino acids 7-96, of human CALB1 protein. The exact sequence is proprietary. |
| Isotype | IgG1 |
| Molecular Weight | 52 kDa |
| Target | Calbindin |
| Specificity | The family of EF-hand type Ca2+-binding proteins includes Calbindin D28K, Calbindin D9K, S-100 (also designated oncomodulin). Calbindin D28K, also known as calbindin, CALB1, D-28K or vitamin D-dependent calcium-binding protein, is a 261-amino acid protein with 6 EF-hand domains, 4 of which are active calcium-binding domains. Expressed in brain, ovary, uterus, testis, pancreas, liver, kidney and intestine, Calbindin D28K acts as a calcium-buffering agent and alters the activity of the plasma membrane ATPase. In neuronal cells, Calbindin D28K modulates calcium channel activity, calcium transients and intrinsic neuronal firing activity. Also, Calbindin D28K has been implicated to play a role in apoptosis and microtubule function. |
| Reactivity | Human |
| Applications | ELISA |
| Form | Liquid |
| Diluent Buffer | Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide. |
| Concentration | 200 µg/ml |
| Storage | Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. |
| Supplier | Antibodies.com |
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