| Product Name | Anti-Caldesmon Antibody [rCALD1/820] - BSA and Azide free |
|---|---|
| Description | Recombinant mouse monoclonal [rCALD1/820] antibody to Caldesmon. |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | rCALD1/820 |
| Conjugate | Unconjugated |
| Immunogen | Recombinant full-length human CALD1 protein. |
| Isotype | IgG1 |
| Molecular Weight | 120-150 kDa |
| Target | Caldesmon |
| Specificity | This antibody recognizes a protein of 150kDa, which is identified as the high molecular weight variant of Caldesmon. Two closely related variants of human caldesmon have been identified which are different in their electrophoretic mobility and cellular distribution. The h-caldesmon variant (120 150kDa) is predominantly expressed in smooth muscle whereas l-caldesmon (70 80kDa) is found in non- muscle tissue and cells. Neither of the two variants has been detected in skeletal muscle. This antibody recognizes only the 150kDa variant (h-caldesmon) in Western blots of human aortic media extracts and is unreactive with fibroblast extracts from cultivated human foreskin. Caldesmon is a developmentally regulated protein involved in smooth muscle and non-muscle contraction. |
| Reactivity | Human |
| Applications | IHC, WB |
| Working Dilutions | WB: 1-2 µg/ml, IHC-P: 0.25-0.5 µg/ml |
| Form | Liquid |
| Diluent Buffer | Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free. |
| Concentration | 1 mg/ml |
| Storage | Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. |
| Supplier | Antibodies.com |
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