Anti-Calgranulin B (Macrophage Marker), Monoclonal Antibody
| Product Name | Anti-Calgranulin B (Macrophage Marker), Monoclonal Antibody |
|---|---|
| Description | Recognizes a 12-14kDa doublet of Calgranulin A/B (also known as S100A8/A9 or MRP-8/14); expressed by granulocytes, monocytes and by tissue macrophages._The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. Altered expression of this protein is associated with the disease cystic fibrosis. This monoclonal antibody reacts with neutrophils, monocytes, macrophages, and squamous mucosal epithelia and has been shown as an important marker for identifying macrophages in tissue sections. |
| Synonyms | Leukocyte L1 complex heavy chain, CAGB, Calgranulin-B, Calprotectin L1H subunit, CFAG, CGLB, Cystic fibrosis antigen B, L1AG, Migration inhibitory factor-related protein 14, MRP14, S100A9, S100 calcium-binding protein A9 |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | CAGB/426 |
| Immunogen | Recombinant human CAGB protein |
| Isotype | IgM, kappa |
| Reactivity | Human |
| Applications | FC, IF, IHC |
| Form | 200ug/ml of Ab purified from Bioreactor Concentrate. Prepared in 1mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA at 1.0mg/ml. |
| Gene Id | 6280 (S100A9 / Calgranulin B / MRP-14) |
| Uniprot | P06702 (S100A9 / Calgranulin B / MRP-14) |
| Storage | Antibody with azide - store at 2 to 8°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required. |
| References | Hermani, A., et al. 2005. Calcium-binding proteins S100A8 and S100A9 as novel diagnostic markers in human prostate cancer. Clin. Cancer Res. 11: 5146-5152 |
| Supplier | ARP |
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