Anti-Carbonic Anhydrase IX (Renal Cell Marker), Monoclonal Antibody
| Product Name | Anti-Carbonic Anhydrase IX (Renal Cell Marker), Monoclonal Antibody |
|---|---|
| Description | Recognizes a glycoprotein of ~200kDa, identified as carbonic anhydrase IX (CAIX/gp200). Carbonic Anhydrases (CAs) are members of a large family of zinc metallo-enzymes that catalyze the reversible hydration of carbon dioxide. CAs are involved in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption and the formation of aqueous humor, cerebrospinal fluid, saliva and gastric juice. They show extensive diversity in distribution and in their subcellular localization. CA IX is specifically expressed in clear-cell renal carcinomas. |
| Synonyms | CA-IX, CA9, CAH9_HUMAN, CAIX, Carbonate dehydratase IX, Carbonic anhydrase 9, Carbonic anhydrase IX, Carbonic dehydratase, G250, Membrane antigen MN, P54/58N, pMW1, RCC-associated antigen G250, Renal cell carcinoma-associated antigen G250 |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | CA9/781 |
| Immunogen | Recombinant human CA9 protein |
| Isotype | IgG2b, kappa |
| Reactivity | Equine, Human |
| Applications | FC, IF, IHC, WB |
| Form | 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml. |
| Gene Id | 768 |
| Uniprot | Q16790 |
| Storage | Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required. |
| References | Sly, W.S., et al. 1995. Human Carbonic Anhydrases and Carbonic Anhydrase deficiencies. Annu. Rev. Biochem. 64: 375-401 |
| Supplier | ARP |
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