| Product Name | Anti-Carbonic Anhydrase IX Antibody [CA9/3407] |
|---|---|
| Description | Mouse monoclonal [CA9/3407] antibody to Carbonic Anhydrase IX. |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | CA9/3407 |
| Conjugate | Unconjugated |
| Immunogen | Recombinant fragment, around amino acids 314-410, of human CA9 protein. The exact sequence is proprietary. |
| Isotype | IgG2b |
| Molecular Weight | 55 kDa |
| Target | Carbonic Anhydrase IX |
| Specificity | This antibody recognizes a glycoprotein of ~200kDa, identified as carbonic anhydrase IX (CAIX/gp200). In normal kidney, gp200 is localized along the brush border of the pars convoluta and pars recta segments of the proximal tubule, as well as focally along the luminal surface of Bowmans capsule adjoining the outgoing proximal tubule. Reportedly, gp200 is expressed by 93% of primary and 84% of metastatic renal cell carcinomas. This MAb may be useful in the investigations of carcinomas of proximal nephrogenic differentiation especially those showing tubular differentiation. |
| Reactivity | Human |
| Applications | IHC-P |
| Working Dilutions | IHC-P: 1-2 µg/ml |
| Form | Liquid |
| Diluent Buffer | Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide. |
| Concentration | 200 µg/ml |
| Storage | Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. |
| Supplier | Antibodies.com |
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