Anti-Carcinoembryonic Antigen Antibody [SPM506] - BSA and Azide free
| Product Name | Anti-Carcinoembryonic Antigen Antibody [SPM506] - BSA and Azide free |
|---|---|
| Description | Mouse monoclonal [SPM506] antibody to Carcinoembryonic Antigen. |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | SPM506 |
| Conjugate | Unconjugated |
| Immunogen | Human colon carcinoma extract. |
| Isotype | IgG1 |
| Molecular Weight | 80-200 kDa |
| Target | Carcinoembryonic Antigen |
| Specificity | This antibody recognizes proteins of 80-200kDa, identified as different members of CEA family. CEA is synthesized during development in the fetal gut and is re-expressed in increased amounts in intestinal carcinomas and several other tumors. This MAb does not react with nonspecific cross-reacting antigen (NCA) and with human polymorphonuclear leucocytes. It shows no reaction with a variety of normal tissues and is suitable for staining of formalin/paraffin tissues. CEA is not found in benign glands, stroma, or malignant prostatic cells. Antibody to CEA is useful in detecting early foci of gastric carcinoma and in distinguishing pulmonary adenocarcinomas (60-70% are CEA+) from pleural mesotheliomas (rarely or weakly CEA+). Anti-CEA positivity is seen in adenocarcinomas from the lung, colon, stomach, esophagus, pancreas, gallbadder, urachus, salivary gland, ovary, and endocervix. |
| Reactivity | Monkey, Human |
| Applications | FC, IF, IHC-P |
| Working Dilutions | Flow Cytometry: 0.5-1 µg/million cells, IF: 1-2 µg/ml, IHC-P: 1-2 µg/ml |
| Form | Liquid |
| Diluent Buffer | Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free. |
| Concentration | 1 mg/ml |
| Storage | Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. |
| Supplier | Antibodies.com |
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