| Product Name | Anti-CCR5 Antibody |
|---|---|
| Description | Goat polyclonal antibody to CCR5. |
| Host | Goat |
| Clonality | Polyclonal |
| Conjugate | Unconjugated |
| Immunogen | Synthetic peptide sequence YQVSSPIYDINYYTSEPCQKINVKQIAA corresponding to amino acids 3-30 within the N-terminus of human CD195. |
| Isotype | IgG |
| Target | CCR5 |
| Amino Acid Sequence | YQVSSPIYDINYYTSEPCQKINVKQIAA |
| Protein Length | 28 |
| Specificity | This antibody recognises human CD195, also known as C-C chemokine receptor type 5, CCR5 or C-C CKR-5. CD195 is a 353 amino acid ~37 kDa multiple pass transmembrane glycoprotein and member of the G-protein coupled receptor 1 family, preferentially expressed by a subset of memory Th1 (type 1 helper T) cells. Goat anti human CD195 antibody binds to an epitope within the N-terminal region of CD195.CD195 acts as a high-affinity receptor for several chemotactic chemokines, including MIP-1 alpha (macrophage inflammatory protein 1 alpha), MIP-1 beta, and RANTES (regulated on activation normal T expressed and secreted protein). CD195 is also a major co-receptor for HIV-1 infection, with variations in the CD195 gene, influencing the rate of progression into AIDS. Goat anti human CD195 antibody is suitable for use in immunocytochemistry on human peripheral blood leucocytes. |
| Reactivity | Human, Primate |
| Applications | IHC-Fr, ELISA, IHC-P, WB |
| Working Dilutions | ELISA: 1:50,000, IHC-P: 1:300, WB: 1:1,000 |
| Form | Liquid |
| Diluent Buffer | Supplied in Phosphate Buffered Saline with 0.1% BSA and 0.1% Sodium Azide. |
| Concentration | 1 mg/ml |
| Storage | Store undiluted at -20°C only. Storage in frost free freezers is not recommended. Avoid freeze-thaw cycles. Should this product contain a precipitate we recommend microcentrifugation before use. |
| Supplier | Antibodies.com |
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