| Product Name | Anti-CD11a Antibody [DF1524] - BSA and Azide free |
|---|---|
| Description | Mouse monoclonal [DF1524] antibody to CD11a. |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | DF1524 |
| Conjugate | Unconjugated |
| Immunogen | Human CD11a protein. |
| Isotype | IgG2b |
| Molecular Weight | 180 kDa |
| Target | CD11a |
| Specificity | This antibody recognizes a protein of 180kDa, identified as CD11a (Leucocyte Workshop IV; Code 1524). CD11a complex with the 2 subunit of the integrin family, CD18, to form the cell surface heterodimer, LFA-1 or CD11a /C18 (aLbL). LFA-1 is expressed on all leukocytes including lymphocytes, monocytes, and granulocytes. It is involved in leukocyte adhesion to its ligands including intercellular adhesion molecule-1 (ICAM-1 or CD54), ICAM-2 (CD102), ICAM-3 (CD50) and Telencephalin (TLN) and play a role in most immune/inflammatory responses. This MAb potently blocks LFA-1 dependent homotypic cell aggregation. |
| Reactivity | Human |
| Applications | FC, Functional Studies, IF |
| Working Dilutions | Flow Cytometry: 1-2 µg/million cells, IF: 1-2 µg/ml |
| Form | Liquid |
| Diluent Buffer | Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free. |
| Concentration | 1 mg/ml |
| Storage | Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. |
| Supplier | Antibodies.com |
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