| Product Name | Anti-CD11b Antibody [M1/70.15] (Amethyst Orange) |
|---|---|
| Description | Rat monoclonal [M1/70.15] antibody to CD11b (Amethyst Orange). |
| Host | Rat |
| Clonality | Monoclonal |
| Clone | M1/70.15 |
| Conjugate | AO |
| Immunogen | T cell enriched splenocytes from B10 mice. |
| Isotype | IgG2b |
| Target | CD11b |
| Specificity | This antibody recognises the murine CD11b cell surface antigen also known as the alpha M integrin chain or MAC-1, a differentiation antigen expressed by granulocytes, monocytes, NK cells and tissue macrophages. The expression of CD11b increases during monocyte maturation and expression levels vary on tissue macrophages. Peritoneal macrophages are reported to express higher levels of CD11b than splenic macrophages. Rat anti Mouse CD11b antibody, clone M1/70.15 has been reported to block iC3b binding to its receptor. Rat anti Mouse CD11b antibody, clone M1/70.15 has been reported to as being suitable for use on PLP fixed paraffin embedded tissue but has not been tested for use on formalin fixed tissue. This product is routinely tested in flow cytometry on mouse peritoneal macrophages. |
| Reactivity | Human, Mouse, Rabbit |
| Applications | FC |
| Working Dilutions | Flow Cytometry: 1:50 - 1:50 Pack Size: 0.25 mg 1:200 Pack Size: 0.1 mg |
| Form | Liquid |
| Diluent Buffer | Supplied in Phosphate Buffered Saline with 1% BSA and 0.09% Sodium Azide. |
| Concentration | 100 µg/ml |
| Storage | Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended. This product is photosensitive and should be protected from light. |
| Supplier | Antibodies.com |
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