| Product Name | Anti-CD11c Antibody [BAQ153A] |
|---|---|
| Description | Mouse monoclonal [BAQ153A] antibody to CD11c. |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | BAQ153A |
| Conjugate | Unconjugated |
| Immunogen | Cells from multiple species. |
| Isotype | IgM |
| Target | CD11c |
| Specificity | This antibody recognises bovine CD11c also known as integrin alpha X. CD11c is a receptor for fibrinogen recognizing the G-P-R motif in fibrinogen. It is involved in the cell to cell interaction during inflammatory responses. In addition, it has an important function in adhesion and chemotaxis in monocytes, macrophages and dendritic cells (DCs).In cattle, CD11c+ DCs are a source of the anti-inflammatory cytokine IL-10 during infection by the highly pathogenic foot-and-mouth disease virus (FMDV). IL-10 may be responsible for the reduction in the antigen processing ability of DCs during FMDV infection. Clone BAQ153A reacts with bovine CD11c+ macrophages, DCs and some lymphocytes as shown by IHC and flow cytometry. |
| Reactivity | Bison, Buffalo, Bovine, Goat, Sheep |
| Applications | FC, ICC |
| Working Dilutions | Flow Cytometry: Neat - 1:10, Use 10µl of the suggested working dilution to label 106 cells in 100µl |
| Form | Liquid |
| Diluent Buffer | Supplied in serum free tissue culture medium containing proprietary protein free supplement and 0.09% Sodium Azide. |
| Concentration | 1 mg/ml |
| Storage | Store at 4°C. Do not freeze! Should this product contain a precipitate we recommend microcentrifugation before use. |
| Supplier | Antibodies.com |
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