| Product Name | Anti-CD11c Antibody [CBR-p150/4G1] - BSA and Azide free |
|---|---|
| Description | Mouse monoclonal [CBR-p150/4G1] antibody to CD11c. |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | CBR-p150/4G1 |
| Conjugate | Unconjugated |
| Immunogen | Recombinant human CD11c. |
| Isotype | IgG2a |
| Target | CD11c |
| Specificity | This antibody recognises human CD11c, otherwise known as integrin alpha X chain and leukocyte adhesion receptor p150,95, a ~150 kDa type I transmembrane protein and member of the integrin alpha chain family, expressed by monocytes, macrophages, granulocytes and NK cells, and is a marker for hairy cell leukaemia cells. CD11c combines with the CD18 beta chain (ITGB2) to form the leukocyte specific integrin CR4, acts as a mediator of leukocyte adherence to endothelium, and binds to the ligands CD54 (ICAM1), iC3b and fibrinogen. Mouse anti Human CD11c antibody, clone CBR-p150/4G1 inhibits the binding of CD11c to endothelial cells. Mouse anti Human CD11c antibody, clone CBR-p150/4G1 does not recognize CD11a, CD11b or CD18. |
| Reactivity | Human |
| Applications | IHC-Fr, FA, FC |
| Working Dilutions | IHC-Fr: 5 - 10 µg/ml, Use 10µl of the suggested working dilution to label 1x106 cells in 100µl. |
| Form | Liquid |
| Diluent Buffer | Supplied in Phosphate Buffered Saline. |
| Concentration | 1 mg/ml |
| Storage | Store undiluted at -20°C only. Storage in frost free freezers is not recommended. Avoid freeze-thaw cycles. Should this product contain a precipitate we recommend microcentrifugation before use. |
| Supplier | Antibodies.com |
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