| Product Name | Anti-CD137 Antibody (Biotin) - BSA and Azide free |
|---|---|
| Description | Goat polyclonal antibody to CD137 (Biotin). |
| Host | Goat |
| Clonality | Polyclonal |
| Conjugate | Biotin |
| Immunogen | Recombinant human CD137. |
| Isotype | IgG |
| Target | CD137 |
| Specificity | This antibody recognises human CD137, otherwise known as 4-1BB ligand receptor, a type I transmembrane glycoprotein and member of the tumour necrosis factor receptor superfamily, predominantly expressed by activated T cells, which acts as a receptor for 4-1BB ligand (4-1BBL).Interaction between CD137 and 4-1BBL, acts as a co-stimulatory signal for T cell activation and expansion, and is involved in the generation of cytotoxic T cells (Tc) and in the process of antigen presentation. CD137 also binds to the adaptor proteins TRAF1, 2 and 3 to act as a signal transducer of NF-kappaB activation. |
| Reactivity | Human |
| Applications | ELISA, WB |
| Working Dilutions | ELISA: 0.5 - 2 µg/ml, WB: 0.1 - 0.2 µg/ml |
| Form | Lyophilized |
| Diluent Buffer | Supplied in Phosphate Buffered Saline. |
| Concentration | 100 µg/ml after reconstitution. |
| Storage | Lyophilized: Store at -20°C. Reconstituted: Store undiluted at -20°C, avoid freeze / thaw cycles. Storage in frost free freezers is not recommended. Should this product contain a precipitate we recommend microcentrifugation before use. |
| Supplier | Antibodies.com |
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