Anti-CD15 / FUT4 (Reed-Sternberg Cell Marker), Monoclonal Antibody
| Product Name | Anti-CD15 / FUT4 (Reed-Sternberg Cell Marker), Monoclonal Antibody |
|---|---|
| Description | CD15 plays a role in mediating phagocytosis, bactericidal activity, and chemotaxis. It is present on >95% of granulocytes including neutrophils and eosinophils and to a lesser degree on monocytes. In addition, CD15 is expressed in Reed-Sternberg cells and some epithelial cells. CD15 antibody is very useful in the identification of Hodgkin s disease. CD15 is occasionally expressed in large cell lymphomas of both B and T phenotypes which otherwise have a quite distinct histological appearance. |
| Synonyms | 3 Fucosyl N Acetyl Lactosamine, Alpha (1,3) Fucosyltransferase, Alpha 13 fucosyltransferase FucT, ELAM Ligand Fucosyltransferase, ELFT, FCT3A, Fuc-TIV, Fucosyltransferase 4 Alpha 1 3 Fucosyltransferase Myeloid Specific, Fucosyltransferase 4, Galactoside 3 L Fucosyltransferase, Lewis X, LeX, SSEA1, Stage Specific Embryonic Antigen 1 |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | FUT4/815 |
| Immunogen | Purified human neutrophils |
| Isotype | IgM, kappa |
| Reactivity | Human, Mouse, Rat |
| Applications | FC, IF, IHC |
| Form | 200ug/ml of Ab purified from Bioreactor Concentrate. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml. |
| Gene Id | 2526 |
| Uniprot | P22083 |
| Storage | Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required. |
| References | Hakomori, S. 1992. LeX and related structures as adhesion molecules. Histochem. J. 24: 771-776. |
| Supplier | ARP |
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