| Product Name | Anti-CD161 Antibody [10/78] (PE) |
|---|---|
| Description | Mouse monoclonal [10/78] antibody to CD161 (PE). |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | 10/78 |
| Conjugate | PE |
| Immunogen | Purified splenic NK cells from the LEW rat strain. |
| Isotype | IgG1 |
| Target | CD161 |
| Specificity | This antibody recognises the rat Killer cell lectin-like receptor subfamily B protein, also known as NKR-PI or CD161. CD161 is a 233 amino acid ~60 kDa type II single pass protein containing a single C-type lectin domain. CD161 is expressed on rat NK cells and T cell subpopulations. CD161 exists in 2 forms NKR-PIa and NKR-PIb, recognises both forms of CD161. Clone 10/78 competes with another anti CD161 clone, 3.2.3 for binding to antigen. Mouse anti Rat CD161 antibody, clone 10/78 has been successfully employed for the in vivo depletion of rat NK cells in an experimental obesity model. |
| Reactivity | Rat |
| Applications | FC |
| Working Dilutions | Flow Cytometry: Neat - 1:10, Use 10µl of the suggested working dilution to label 106 cells in 100µl |
| Form | Lyophilized |
| Diluent Buffer | Supplied in Phosphate Buffered Saline with 1% BSA, 5% Sucrose, and 0.09% Sodium Azide. |
| Concentration | Reconstitution dependent. |
| Storage | Lyophilized: Store at 4°C. Reconstituted: Store undiluted at 4°C. Do not freeze! This product is photosensitive and should be protected from light. Should this product contain a precipitate we recommend microcentrifugation before use. |
| Supplier | Antibodies.com |
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