| Product Name | Anti-CD20 Antibody [FMC7] (FITC) |
|---|---|
| Description | Mouse monoclonal [FMC7] antibody to CD20 (FITC). |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | FMC7 |
| Conjugate | FITC |
| Immunogen | HRIK cells - human B-Lymphoblastoid line. |
| Isotype | IgM |
| Target | CD20 |
| Specificity | This antibody recognises a glycoprotein antigen of ~105 kDa expressed by B lymphocytes. The FMC7 antigen is expressed by peripheral B lymphocytes. recognises a conformational epitope on the CD20 molecule, most likely a multimeric complex of CD20. Identity of CD20 as the antigen recognized by Mouse anti Human B cells antibody, clone FMC7 was further confirmed by strong recognition of recombinant CD20 expressed in hematopoietic and non-haematopoietic cell lines and abolition of binding in CD20 extracellular domain mutations. The recognized epitope has also been shown to be cholesterol dependent. |
| Reactivity | Human |
| Applications | FC |
| Working Dilutions | Flow Cytometry: Neat, Use 10µl of the suggested working dilution to label 106 cells or 100µl whole blood. |
| Form | Liquid |
| Diluent Buffer | Supplied in TRIS buffered glycine with 0.1% Sodium Azide and 0.2% BSA. |
| Concentration | Lot Specific |
| Storage | Shipped at ambient temperature. Store at 4°C. This product is photosensitive and should be protected from light. |
| Supplier | Antibodies.com |
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