Anti-CD27 (Tumor Necrosis Factor Receptor Superfamily 7), Monoclonal Antibody
Product Name | Anti-CD27 (Tumor Necrosis Factor Receptor Superfamily 7), Monoclonal Antibody |
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Description | Recognizes a protein of a disulfide-linked 120kDa dimer, identified as CD27 (Workshop VI; Code 6T-028). CD27 is expressed on the majority of peripheral T cells, medullary thymocytes, memory-type B cells, and natural killer cells. It is a transmembrane phosphoglycoprotein that belongs to the tumor necrosis factor receptor (TNFR) superfamily. CD27 binds to its ligand CD70, a member of the TNF family, and induces T-cell co-stimulation and B-cell activation. It also interacts with TRAFs and is involved in activation of NFB and SAPK/JNK and induces apoptosis. |
Synonyms | LPFS2, S152, T cell activation antigen S152, T-cell activation antigen CD27, T14, TNFRSF7, TNFSF7, Tp55, Tumor necrosis factor receptor superfamily member 7 |
Host | Mouse |
Clonality | Monoclonal |
Clone | 203.6 |
Immunogen | Sezary cells |
Isotype | IgG3, kappa |
Reactivity | Human |
Applications | FC, IF |
Form | 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml. |
Gene Id | 939 |
Uniprot | P26842 |
Storage | Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required. |
References | Kishimoto T et al. (eds) Leukocyte Typing VI. P67-71, Garland Publishing, New York, 1997 |
Supplier | ARP |
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