| Product Name | Anti-CD3 Antibody [CA17.2A12] (FITC) |
|---|---|
| Description | Mouse monoclonal [CA17.2A12] antibody to CD3 (FITC). |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | CA17.2A12 |
| Conjugate | FITC |
| Immunogen | Affinity enriched TCR/CD3 membrane proteins isolated from thymocytes and the T cell line CLGL-90. |
| Isotype | IgG1 |
| Target | CD3 |
| Specificity | This antibody recognises the canine CD3 cell surface antigen, expressed by thymocytes and mature T lymphocytes. CD3 is engaged in the surface expression of the T-cell antigen receptor (TCR) and the signal transduction pathway resulting from MHC ligand binding to the TCR. CD3 is made up of a number of invariant subchains of the immunoglobulin superfamily. Mouse anti Dog CD3 clone CA17.2A12 is a valuable flow cytometric and immunohistologic tool for canine lymphoma detection of T-cell origin. |
| Reactivity | Canine |
| Applications | FC |
| Working Dilutions | Flow Cytometry: Neat - 1:10, Use 10µl of the suggested working dilution to label 106 cells or 100µl whole blood. Note: MCA1774F should not be used with MCA1781PE (mouse anti canine B-cells), in dual colour FC, due to non-specific interactions between the two reagents. |
| Form | Liquid |
| Diluent Buffer | Supplied in Phosphate Buffered Saline with 1% BSA and 0.09% Sodium Azide. |
| Concentration | 100 µg/ml |
| Storage | Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended. This product is photosensitive and should be protected from light. |
| Supplier | Antibodies.com |
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