| Product Name | Anti-CD3 epsilon Antibody [APA1/1] (FITC) |
|---|---|
| Description | Mouse monoclonal [APA1/1] antibody to CD3 epsilon (FITC). |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | APA1/1 |
| Conjugate | FITC |
| Immunogen | Human CD3 proteins isolated and purified from thymus. |
| Isotype | IgG1 |
| Target | CD3 epsilon |
| Specificity | This antibody recognizes an activation-dependent intracellular epitope of CD3 epsilon. Exposure of the epitope precedes CD3 phosphorylation and the recruitment and activation of ZAP70, which initiates the signaling cascade produced by T-cell activation. This antibody provides the earliest known marker for TCR-mediated T cell activation. |
| Reactivity | Human, Mouse |
| Applications | FC |
| Working Dilutions | Flow Cytometry: 1 µg/ml |
| Form | Liquid |
| Diluent Buffer | Supplied in Phosphate Buffered Saline with 15 mM Sodium Azide. |
| Concentration | 0.1 mg/ml |
| Storage | Store in the dark at 2-8°C. Do not freeze! |
| Supplier | Antibodies.com |
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