| Product Name | Anti-CD3 epsilon Antibody [B-B12] |
|---|---|
| Description | Mouse monoclonal [B-B12] antibody to CD3 epsilon. |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | B-B12 |
| Conjugate | Unconjugated |
| Immunogen | Human T cell leukemia cells. |
| Isotype | IgG1 |
| Molecular Weight | 20 kDa |
| Target | CD3 epsilon |
| Specificity | This antibody recognizes the epsilon-chain of CD3, which consists of five different polypeptide chains (designated as gamma, delta, epsilon, zeta, and eta) with MW ranging from 16-28kDa. CD3 is expressed, typically at high levels, on peripheral T cells and majority of T cell neoplasms. Thymocytes express CD3 at different level on the cell surface in the course of differentiation and, in cortical thymus, CD3 is predominantly Intracytoplasmic. The CD3 complex is closely associated at the lymphocyte cell surface with T cell antigen receptor (TCR) and is involved in transducing antigen-recognition signals into cytoplasm of T cells and in regulating the cell surface expression of the TCR complex. |
| Reactivity | Human |
| Applications | FC, IF |
| Working Dilutions | Flow Cytometry: 1-2 µg/million cells, IF: 1-2 µg/ml |
| Form | Liquid |
| Diluent Buffer | Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide. |
| Concentration | 200 µg/ml |
| Storage | Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. |
| Supplier | Antibodies.com |
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