| Product Name | Anti-CD30 Antibody [G05-2D2] |
|---|---|
| Description | Mouse monoclonal [G05-2D2] antibody to CD30. |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | G05-2D2 |
| Conjugate | Unconjugated |
| Immunogen | E. coli derived recombinant human full length CD30 (Phe19-Lys595). |
| Isotype | IgG1 |
| Target | CD30 |
| Specificity | This antibody recognises CD30 also known as Tumor Necrosis Factor Receptor Super Family member 8, CD30L receptor and Ki-1 antigen. CD30 is a 120 kDa transmembrane glycoprotein that belongs to the tumor necrosis factor receptor superfamily. CD30 is expressed on small subsets of activated T and B lymphocytes and a range of lymphoid neoplasms. Upon binding of its ligand CD30L, CD30 undergoes trimerization and recruits TNFR-associated factor (TRAF) and TRAF binding proteins generating a signaling complex which can then mediate MAPK and NF?B signaling. In this way, CD30 signaling is able to regulate peripheral T cell responses, controls T cell survival, down regulates cytolitic capacity and regulates thymocyte survival. The purified Mouse anti Human CD30 antibody, clone G05-2D2 (MCA62670GA) can be used as a capture antibody in a sandwich ELISA with the biotinylated Mouse anti Human CD30 antibody, clone D02-6E11 (MCA6271B) as the detection antibody. |
| Reactivity | Human |
| Applications | ELISA |
| Working Dilutions | ELISA: 1 µg/ml |
| Form | Liquid |
| Diluent Buffer | Supplied in Phosphate Buffered Saline with 0.09% Sodium Azide. |
| Concentration | 1 mg/ml |
| Storage | Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended. |
| Supplier | Antibodies.com |
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