| Product Name | Anti-CD32 Antibody [CCG36] (PE) |
|---|---|
| Description | Mouse monoclonal [CCG36] antibody to CD32 (PE). |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | CCG36 |
| Conjugate | PE |
| Immunogen | Bovine Fc gamma RII-transfected COS7 cells. |
| Isotype | IgG1 |
| Target | CD32 |
| Specificity | This antibody recognises the bovine homologue of human CD32, one of a group of Fc receptors belonging to the immunoglobulin superfamily and involved in phagocytosis of opsonized microbes. Bovine CD32 is a single pass type 1 membrane protein of approximately 32kDa, expressed on the cell surface of most cells including B-lymphocytes, monocytes, neutrophils and afferent veiled lymph dendritic cells Chattha, K. et al. 2010. It has been shown that expression of bovine CD32 is higher on macrophages than on neutrophils.CD32 can function in an inhibitory capacity to antibody production and is the low affinity Fc receptor for IgG (FcRII), binding to the Fc region of immunoglobulin gamma Chattha et al. 2009.recognises ovine CD32 while clone CCG39 recognises only bovine CD32. |
| Reactivity | Bovine, Sheep |
| Applications | FC |
| Working Dilutions | Flow Cytometry: Neat, Use 10µl of the suggested working dilution to label 1x106 cells in 100µl |
| Form | Lyophilized |
| Diluent Buffer | Supplied in Phosphate Buffered Saline with 1% BSA, 5% Sucrose, and 0.09% Sodium Azide. |
| Concentration | Reconstitution dependent. |
| Storage | Lyophilized: Store at 4°C. Reconstituted: Store undiluted at 4°C. Do not freeze! This product is photosensitive and should be protected from light. |
| Supplier | Antibodies.com |
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