| Product Name | Anti-CD4 Antibody (E9) (06-1034-2) |
|---|---|
| Description | This gene encodes a membrane glycoprotein of T lymphocytes that interacts with major histocompatibility complex class II antigenes and is also a receptor for the human immunodeficiency virus. This gene is expressed not only in T lymphocytes, but also in B cells, macrophages, and granulocytes. It is also expressed in specific regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene. Mouse monoclonal Antibody to Human CD4 clone E9 |
| Synonyms | CD4 |
| Clone | E9 |
| Immunogen | Purified Human CD4+ peripheral blood T cells |
| Isotype | IgG2b |
| Specificity | Clone E9 detects Human CD4 |
| Reactivity | Human |
| Applications | FC, IHC |
| Form | Affinity Purified, in PBS containing 0.5% BSA and 0.1% Sodium Azide |
| Storage | 2-8C for immediate use; or at -20C (aliquot) Avoid freeze-thaw cycles |
| Background | This gene encodes a membrane glycoprotein of T lymphocytes that interacts with major histocompatibility complex class II antigenes and is also a receptor for the human immunodeficiency virus. This gene is expressed not only in T lymphocytes, but also in B cells, macrophages, and granulocytes. It is also expressed in specific regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene. |
| Supplier | ARP |
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