| Product Name | Anti-CD41 Monoclonal Antibody, Culture Supernatant |
|---|---|
| Description | Mouse monoclonal antibody to human CD41-Culture supernatant. Integrin alpha 2b (CD41) is a 135 kDa calcium-dependent glycoprotein consisting of a heavy chain (GPIIb alpha; 120kDa) and a light chain (GPIIb beta; 23kDa) linked by a single disulphide bond. The alpha chain contains four calcium-binding sites and is entirely extracellular, while the beta chain has extracellular, transmembrane and cytoplasmic domains. |
| Synonyms | CD41, Integrin alpha 2b, 135 kDa calcium-dependent glycoprotein consisting of GPIIb alpha and GPIIb beta |
| Clonality | Monoclonal |
| Clone | 5B12 |
| Immunogen | 5B12 was made in response to immunisation with normal human platelets. |
| Isotype | Mouse IgG1 kappa light chain |
| Reactivity | Human |
| Applications | IF |
| Form | Culture Supernatant |
| Storage | 2-8C for immediate use, or at -2°C (aliquot) |
| References | 1. Sun QH, Newman PJ. CD guide. CD41. In: Kishimoto T, Kikutani H, von dem Borne AEG, Goyert SM, Mason DY, Miyasaka M, et al., editors. Leucocyte typing VI. White cell differentiation antigens. Proceedings of the 6th International Workshop and Conference; 1996 Nov 10-14; Kobe, Japan . New York, London: Garland Publishing Inc.; 1997. p. 1139. 2. Vinci G, Tabilio A, Deschamps JF, van Haeke D, Henri A, Guichard J, et al. Immunological study of in vitro maturation of human megakaryocytes. Br J Haematol 1984; 56:589-605. 3. Honda S, Felding-Habermann B, Loftus J, Annis D, Kunicki TJ. CD41/CD61 cluster workshop report: localization of epitopes on integrins aIIb beta 3å (CD41/CD61) and av beta 3å (CD51/CD61). In: Schlossman SF, Boumsell L, Gilks W, Harlan JM, Kishimoto T, Morimoto C, et al., editors. Leucocyte typing V. White cell differentiation antigens. Proceedings of the 5th International Workshop and Conference; 1993 Nov 3-7; Boston , USA . Oxford , New York , Tokyo : Oxford University Press; 1995. p. 1293-8. 4. Kiefel, V., Santoso, S., Weisheit, M. & Mueller-Eckhardt, C. (1987) Monoclonal antibody-specific immobilization of platelet antigens (MAIPA): a new tool for the identification of platelet reactive antibodies. Blood, 70, 1722-1726. |
| Supplier | ARP |
All Research Products are sold for laboratory RESEARCH USE ONLY and ARE NOT TO BE USED FOR HUMAN OR ANIMAL THERAPEUTIC OR DIAGNOSTIC APPLICATIONS. The information presented is believed to be accurate; however, said information and products are offered without warranty or guarantee since the ultimate conditions of use and the variability of the materials treated are beyond our control. Nothing disclosed herein is to be construed as a recommendation to use our products in violation of any patents. ARP American Research Products, Inc. does not submit its products for regulatory review by any government body or other organization, and we do not validate them for clinical, therapeutic or diagnostic use, or for safety and effectiveness. You are solely responsible for making sure that the way you use the products complies with applicable laws, regulations and governmental policies and for obtaining all necessary approvals, intellectual property rights, licenses and permissions that you may need related to your use. Under no circumstances shall ARP American Research Products, Inc. be liable for damages, whether consequential, compensatory, incidental or special, strict liability or negligence, breach of warranty or any other theory arising out of the use of the products available from ARP American Research Products, Inc. Nothing contained herein warrants that the use of the products will not infringe on the claims of any patents covering the product itself or the use thereof in combination with other products or in the operation of any process. ARP American Research Products, Inc. disclaims any and all representations or warranties of any kind whatsoever, express or implied, including without limitation any implied warranties of merchantability or fitness for a particular purpose, of non-infringement, or regarding results obtained through the use of any product, whether arising from a statute or otherwise in law or from a course of performance, dealing or usage of trade.
