| Product Name | Anti-CD44v6 Antibody [CD44V6/2496] - BSA and Azide free |
|---|---|
| Description | Mouse monoclonal [CD44V6/2496] antibody to CD44v6. |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | CD44V6/2496 |
| Conjugate | Unconjugated |
| Immunogen | Recombinant fragment corresponding to the v6 domain of human CD44. |
| Isotype | IgG1 |
| Molecular Weight | 80-95 kDa |
| Target | CD44v6 |
| Specificity | This antibody recognizes an epitope encoded by exon v3 on the variant portion of human CD44. The CD44 molecule belongs to a family of cellular adhesion molecules found on a wide range of normal and malignant cells in epithelial, mesothelial and hemopoiesis tissues. CD44 is a single gene with 20 exons, of which 10 are normally expressed to encode the basic CD44 (H-CAM) molecule. The additional 10 exons (v1 to v10) are only expressed by alternative splicing of the nuclear RNA.The expression of specific cell adhesion molecule CD44 splice variants has been reported to be associated with metastasis in certain human malignancies. |
| Reactivity | Human |
| Applications | IHC-P |
| Working Dilutions | IHC-P: 1-2 µg/ml |
| Form | Liquid |
| Diluent Buffer | Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free. |
| Concentration | 1 mg/ml |
| Storage | Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. |
| Supplier | Antibodies.com |
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