| Product Name | Anti-CD55 Antibody [Bu14] |
|---|---|
| Description | Mouse monoclonal [Bu14] antibody to CD55. |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | Bu14 |
| Conjugate | Unconjugated |
| Isotype | IgG1 |
| Target | CD55 |
| Specificity | This antibody recognises human CD55, also known as Decay Accelerating Factor (DAF). CD55 is a glycosylphosphatylinositol (GPI) anchored type I surface protein which prevents complement mediated lysis of autologous cells. CD55 functions to limit the formation and accelerate the decay of C3/C5-convertases from the classic and alternative pathway.The molecular weight of CD55 varies between ~50 and 100 kDa dependent on cell type. Alternative transcripts can lead to soluble DAF, which is detectable in plasma, tears, saliva, urine and cerebrospinal fluid. CD55 acts as a ligand for CD97 and is an entry receptor for Echovirus and Coxsackie B virus. CD55 has been linked to many diseases including multiple sclerosis, rheumatoid arthritis and cancer development. |
| Reactivity | Human |
| Applications | FC |
| Working Dilutions | Flow Cytometry: Neat - 1:200, Use 10µl of the suggested working dilution to label 1x106 cells in 100µl. |
| Form | Liquid |
| Diluent Buffer | Supplied in Phosphate Buffered Saline with 0.09% Sodium Azide. |
| Concentration | 1 mg/ml |
| Storage | Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended. |
| Supplier | Antibodies.com |
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