| Product Name | Anti-CD6 / T12 Antibody [rC6/372] |
|---|---|
| Description | Recombinant mouse monoclonal [rC6/372] antibody to CD6 / T12. |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | rC6/372 |
| Conjugate | Unconjugated |
| Immunogen | Recombinant full-length human CD6 protein. |
| Isotype | IgG1 |
| Molecular Weight | 90-130 kDa |
| Target | CD6 / T12 |
| Specificity | CD6 is a type I transmembrane glycoprotein that contains a 24-amino acid signal sequence, three extracellular scavenger receptor cysteine-rich (SRCR) domains, a membrane-spanning domain and a 44-amino acid cytoplasmic domain. The CD6 glycoprotein is tyrosine phosphorylated during TCR-mediated T cell activation. CD6 shows significant homology to CD5. CD6 is present on mature thymocytes, peripheral T cells and a subset of B cells. Antibodies to CD6 are used to deplete T cells from bone marrow transplants to prevent graft versus host disease. |
| Reactivity | Human |
| Applications | IHC-P |
| Working Dilutions | IHC: 1-2 µg/ml |
| Form | Liquid |
| Diluent Buffer | Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide. |
| Concentration | 200 µg/ml |
| Storage | Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. |
| Supplier | Antibodies.com |
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