Anti-CD61 / Integrin beta-3 (Platelet Marker), Monoclonal Antibody
| Product Name | Anti-CD61 / Integrin beta-3 (Platelet Marker), Monoclonal Antibody |
|---|---|
| Description | Reacts with human integrin beta3 (GPIIIa, vitronectin receptor beta chain). The protein detectable is a complex of CD41 and CD61.The apparent molecular weight of the GPIIIa by SDS-PAGE is 105kDa reduced and 90kDa unreduced. Ligands are fibronectin, fibrinogen, von Willebrand factor, vitronectin and thrombospondin. Residues 237-248 of GPIIIa or CD61 are critical in adhesive protein binding._ |
| Synonyms | BDPLT2, GP3A, GPIIIa, GT, HPA 1, HPA 4, Integrin beta-3, ITGB3, NAIT, Platelet fibrinogen receptor beta subunit, Platelet glycoprotein IIIa, PTP |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | 25E11. |
| Immunogen | Normal blood mononuclear cells activated by mixed lymphocyte reaction |
| Isotype | IgM, kappa |
| Reactivity | Human |
| Applications | FC, IF |
| Form | 200ug/ml of Ab purified from Bioreactor Concentrate. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml. |
| Gene Id | 3690 |
| Uniprot | P05106 |
| Storage | Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required. |
| References | McMichael AJ et al. (eds) Leukocyte Typing III, Oxford University Press, Oxford, 1987.Schlossman S. et al. (eds) Leukocyte Typing V, Oxford University Press, Oxford, 1995 |
| Supplier | ARP |
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