| Product Name | Anti-CD62P Polyclonal Antibody |
|---|---|
| Description | P-Selectin, also called CD62, GRMP, GMP140 is a 140-kD adhesion molecule, expressed at the surface of activated cells, that mediates the interaction of activated endothelial cells or platelets with leukocytes. The P-Selectin gene is mapped on 1q24.2. P-selectin plays an essential role in the initial recruitment of leukocytes(white blood cells) to the site of injury during inflammation. P-selectin is also very important in the recruitment and aggregation of platelets at areas of vascular injury. In quiescent platelet, P-selectin is located on the inner wall of alpha-granules. Sorting nexin-17 interacts with the cytosolic domain of P-selectin and suggested that SNX17 may function in the intracellular trafficking of P-selectin. P-selectin expression was found to be significantly and positively correlated with carotid artery stiffness and wall thickness, and the percentage of P-selectin-positive platelets was significantly higher in patients with carotid plaque. Rabbit IgG polyclonal antibody for P-selectin(SELP) detection. Tested with WB, IHC-P in Human. |
| Synonyms | Antigen CD62 antibody, CD62 antibody, CD62 antigen-like family member P antibody, CD62P antibody, CD62P antigen antibody, FLJ45155 antibody, GMP 140 antibody, GMP-140 antibody, GMP140 antibody, GMRP antibody, Granule membrane protein 140 antibody, Granule membrane protein 140kDa antibody, Granulocyte membrane protein antibody, GRMP antibody, LECAM 3 antibody, LECAM3 antibody, Leukocyte endothelial cell adhesion molecule 3 antibody, Leukocyte-endothelial cell adhesion molecule 3 antibody, LYAM3_HUMAN antibody, P Selectin antibody, P-selectin antibody, PADGEM antibody, Platelet activation dependent granule external membrane protein antibody, Platelet activation dependent granule-external membrane protein antibody, Platelet alpha granule membrane protein antibody, PSEL antibody, Selectin P(granule membrane protein 140kDa antigen CD62) antibody, Selectin P(granule membrane protein 140kDa, antigen CD62) antibody, SELP antibody |
| Host | Rabbit |
| Clonality | Polyclonal |
| Immunogen | A synthetic peptide corresponding to a sequence at the N-terminus of human CD62P(49-66aa KAYSWNISRKYCQNRYTD). |
| Isotype | Rabbit IgG |
| Specificity | No cross reactivity with other proteins. |
| Reactivity | Human |
| Applications | IHC, WB |
| Form | Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3. |
| Reconstitution | Add 0.2ml of distilled water will yield a concentration of 500ug/ml. |
| Uniprot | P16109 |
| Supplier | ARP |
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