| Product Name | Anti-CD63 Antibody [LAMP3/7369] - BSA and Azide free |
|---|---|
| Description | Mouse monoclonal [LAMP3/7369] antibody to CD63. |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | LAMP3/7369 |
| Conjugate | Unconjugated |
| Immunogen | Recombinant fragment (around Amino Acids 100-200) of human CD63 protein. The exact sequence is proprietary. |
| Isotype | IgG2 |
| Molecular Weight | 26 kDa (core protein) / 30-60 kDa (glycosylated) |
| Target | CD63 |
| Specificity | CD63 is expressed on activated platelets, monocytes and macrophages, and is weakly expressed on granulocytes, T cell and B cells. It is located on the basophilic granule membranes and on the plasma membranes of lymphocytes and granulocytes. CD63 is a member of the TM4 superfamily of leukocyte glycoproteins that includes CD9, CD37 and CD53, which contain four transmembrane regions. CD63 may play a role in phagocytic and intracellular lysosome-phagosome fusion events. CD63 deficiency is associated with Hermansky-Pudlak syndrome and is strongly expressed during the early stages of melanoma progression. |
| Reactivity | Human |
| Applications | FA, FC, IF, IHC-P, IP |
| Working Dilutions | Functional studies, IP: 1-2 µg per 100-500ug of total protein (1ml of cell lysate), Flow Cytometry: 1-2 µg/million cells, IF: 1-2 µg/ml, IHC: 1-2 µg/ml |
| Form | Liquid |
| Diluent Buffer | Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free. |
| Concentration | 1 mg/ml |
| Storage | Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. |
| Supplier | Antibodies.com |
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