Anti-CD66b (granulocytes) Monoclonal Antibody, Culture Supernatant
| Product Name | Anti-CD66b (granulocytes) Monoclonal Antibody, Culture Supernatant |
|---|---|
| Description | Mouse monoclonal antibody to human CD66b (granulocytes)-Culture supernatant. The CD66b antigen, a member of the immunoglobulin (Ig) superfamily, is a 95-100 kDa membrane bound protein encoded by a gene located on chromosome 19. The molecular structure of CD66b reveals a leader sequence of 34 amino acids (aa), an extracellular region of 284 aa and a 29aa hydrophobic domain replaced by GPI. CD66b has 2 Ig C2 domains and 1 IgG-V like domain. The CD66b antigen is expressed on granulocytes. CD66b exhibits only heterotypic adhesion with CD66c with no homophilic activity, suggesting the possibility that CD66b plays a role in the interaction between granulocytes or between granulocytes and epithelial cells. |
| Synonyms | CD66b antigen, CD66b, CD-66b |
| Clonality | Monoclonal |
| Clone | BIRMA 17C |
| Immunogen | BIRMA 17C was produced from a mouse hybridoma derived from the fusion of Balb/c spleen cells with X63Ag8.653 myeloma cells. |
| Isotype | Mouse IgG1 kappa light chain |
| Reactivity | Human |
| Applications | FC, IF, WB |
| Form | Culture Supernatant |
| Storage | 2-8C for immediate use, or at -2°C (aliquot) |
| References | 1. Skubitz KM. et al, (Review) PROW CD66b (1999). 2. Skubitz KM. et al, (1997) Leucocyte Typing VI CD66 family workshop panel report p992-1000: sixth international workshop and conference on human leucocyte differentiation antigens, Japan, 1996 Garland Publishing Inc. |
| Supplier | ARP |
All Research Products are sold for laboratory RESEARCH USE ONLY and ARE NOT TO BE USED FOR HUMAN OR ANIMAL THERAPEUTIC OR DIAGNOSTIC APPLICATIONS. The information presented is believed to be accurate; however, said information and products are offered without warranty or guarantee since the ultimate conditions of use and the variability of the materials treated are beyond our control. Nothing disclosed herein is to be construed as a recommendation to use our products in violation of any patents. ARP American Research Products, Inc. does not submit its products for regulatory review by any government body or other organization, and we do not validate them for clinical, therapeutic or diagnostic use, or for safety and effectiveness. You are solely responsible for making sure that the way you use the products complies with applicable laws, regulations and governmental policies and for obtaining all necessary approvals, intellectual property rights, licenses and permissions that you may need related to your use. Under no circumstances shall ARP American Research Products, Inc. be liable for damages, whether consequential, compensatory, incidental or special, strict liability or negligence, breach of warranty or any other theory arising out of the use of the products available from ARP American Research Products, Inc. Nothing contained herein warrants that the use of the products will not infringe on the claims of any patents covering the product itself or the use thereof in combination with other products or in the operation of any process. ARP American Research Products, Inc. disclaims any and all representations or warranties of any kind whatsoever, express or implied, including without limitation any implied warranties of merchantability or fitness for a particular purpose, of non-infringement, or regarding results obtained through the use of any product, whether arising from a statute or otherwise in law or from a course of performance, dealing or usage of trade.
