Anti-CD71 / Transferrin Receptor (TFRC), Monoclonal Antibody
| Product Name | Anti-CD71 / Transferrin Receptor (TFRC), Monoclonal Antibody |
|---|---|
| Description | It recognizes a ~90-95kDa protein which is identified as cell surface transferrin receptor (CD71), a disulfide-bonded homodimeric glycoprotein of 180-190kDa. This monoclonal antibody is highly specific to CD71 and shows no cross-reaction with other related proteins. Ligand for transferrin receptor is the serum iron transport protein, transferrin. This receptor is broadly distributed in carcinomas, sarcomas, leukemias, and lymphomas. CD71/Transferrin receptor has been reported to be associated with cell proliferation in both normal and neoplastic tissues and useful in predicting clinical behavior or response to therapy in a number of malignancies including breast cancer. |
| Synonyms | Mtvr-1, p90, TFR1, TFRC transferrin receptor (p90 CD71), TRFR |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | TFRC/1149 |
| Immunogen | Recombinant human TFRC protein |
| Isotype | IgG1, kappa |
| Reactivity | Human |
| Applications | FC, IF, WB |
| Form | 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml. |
| Gene Id | 7037 |
| Uniprot | P02786 |
| Storage | Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required. |
| References | Van de Rijna M, Geurts van Kessel AHM, Kroezen V, van Agthoven AJ, Verstijnen K, Terhorst C, Hilgers J: Cytogenet Cell Genet 1983;36:525-531.Oudermans et al. Cancer, 1986; 58:1252.K. Moolenaar et al. Cancer research 50,1102-1106, 1990 |
| Supplier | ARP |
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