| Product Name | Anti-CD79b Antibody [CD79b/4960] |
|---|---|
| Description | Mouse monoclonal [CD79b/4960] antibody to CD79b. |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | CD79b/4960 |
| Conjugate | Unconjugated |
| Immunogen | Recombinant fragment of human CD79b protein. The exact sequence is proprietary. |
| Isotype | IgG1 |
| Molecular Weight | 39 kDa |
| Target | CD79b |
| Specificity | CD79 (also designated Ig chains, designated CD79B or B29. The B cell antigen receptor complex (BCR) is formed by the association of CD79 with a membrane immunoglobulin, such as IgM or IgD. The membrane immunoglobulins IgM and IgD achieve surface expression and antigen presentation function in response to CD79 association. The cytoplasmic tails of both CD79A and CD79B contain an ITAM (immuno-receptor tyrosine-based activation) motif, which acts to initiate the BCR signaling reactions by binding to and activating tyrosine kinases. |
| Reactivity | Human |
| Applications | ELISA, IHC-P |
| Working Dilutions | ELISA: 2-4 µg/ml for coating, IHC: 1-2 µg/ml |
| Form | Liquid |
| Diluent Buffer | Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide. |
| Concentration | 200 µg/ml |
| Storage | Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. |
| Supplier | Antibodies.com |
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