| Product Name | Anti-CD8 Antibody [YCATE55.9] (PE) |
|---|---|
| Description | Rat monoclonal [YCATE55.9] antibody to CD8 (PE). |
| Host | Rat |
| Clonality | Monoclonal |
| Clone | YCATE55.9 |
| Conjugate | PE |
| Immunogen | Canine CD8 alpha chimaeric human IgG1 Fc fusion protein. |
| Isotype | IgG1 |
| Target | CD8 |
| Specificity | This antibody recognises a rat cell line transfected with cDNA for canine CD8a and blocks MHC class I dependant T-cell responses in vitro and in vivo.Rat anti Dog CD8, clone YCATE55.9 has been shown to deplete circulating CD8+ T cells when administered to dogs in vivo. Reduced levels of circulating CD8+ T cells has been associated with decreased survival times for dogs with osteosarcoma. |
| Reactivity | Canine |
| Applications | FC |
| Working Dilutions | Flow Cytometry: Neat, Use 10µl of the suggested working dilution to label 1 x 106 cells in 100µl |
| Form | Lyophilized |
| Diluent Buffer | Supplied in Phosphate Buffered Saline with 1% BSA, 5% Sucrose, and 0.09% Sodium Azide. |
| Concentration | Reconstitution dependent. |
| Storage | Lyophilized: Store at 4°C. Reconstituted: Store undiluted at 4°C. Do not freeze! This product is photosensitive and should be protected from light. Should this product contain a precipitate we recommend microcentrifugation before use. |
| Supplier | Antibodies.com |
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