Anti-CD90 / Thy1 (Anti-Mouse) (Stromal / Mesenchymal Marker), Monoclonal Antibody
| Product Name | Anti-CD90 / Thy1 (Anti-Mouse) (Stromal / Mesenchymal Marker), Monoclonal Antibody |
|---|---|
| Description | Recognizes a protein of 25kDa, identified as mouse Thy-1 (also known as CD90). It is a glycosyl phosphatidylinositol-anchored surface glycoprotein. CD90 is a member of the immunoglobulin superfamily. It may contribute to inhibition of proliferation/differentiation of hematopoietic stem cells and neuron memory formation in the CNS. It consists of a single Ig domain (112 amino acids; 25-35kDa) inserted into the cell membrane via a GPI anchor. Thy-1 is expressed mainly on brain and lymphoid tissues including thymocytes, Peripheral T-cells, and some intraepithelial T-lymphocytes. Thy-1 may play a role in T cell activation, development and function of nervous system, and apoptosis. |
| Synonyms | CD90, Theta antigen, Thy 1 cell surface antigen, Thy 1 membrane glycoprotein, Thy 1.2, Thy-1 antigen, Thy-1 membrane glycoprotein, Thy1, Thy1 T cell antigen, Thy1.1, Thy1.2, Thymus cell antigen 1, theta |
| Host | Rat |
| Clonality | Monoclonal |
| Clone | IBL-6/23 |
| Immunogen | Mouse EL-4 T cell lymphoma cells |
| Isotype | IgG1, kappa |
| Reactivity | Mouse |
| Applications | FC, IF |
| Form | 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml. |
| Gene Id | 21838 (Mouse) |
| Uniprot | P01831 (Mouse) |
| Storage | Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required. |
| References | Beissert S et al. Impaired cutaneous immune responses in Thy-1-deficient mice. J Immunol 1998, 161(10):5296-302Williams, A.F., and J. Gagnon. 1982. Neuronal cell Thy-1 glycoprotein: Homology with immunoglobulin. Science 216: 696 - 703Fujita N et al. Aggregation of Thy-1 glycoprotein induces thymocyte apoptosis through activation of CPP32-like proteases. Exp Cell Res 1997, 232(2):400-406 Kroczek, R.A., K.C. Gunter, R.N. Germain, and E.M. Shevach. 1986. Thy-1 functions as a signal transduction molecule in T lymphocytes and transfected B lymphocytes. Nature 322: 181 - 184 |
| Supplier | ARP |
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