| Product Name | Anti-CD90.2 / Thy-1.2 (mouse) Monoclonal Antibody |
|---|---|
| Description | CD90 (Thy-1) is an 18-35 kDa GPI-anchored plasma membrane glycoprotein expressed in many cell types, such as in hematopoietic cells and neurons, connective tissues, various fibroblast and stromal cell lines, tumor endothelial cell lines and other. In the mouse, CD90 is expressed mainly on thymocytes and peripheral T lymphocytes. It is involved in T cell activation, cellular adhesion, proliferation and migration, neurite outgrowth, wound healing, apoptosis, and fibrosis. CD90 participates in multiple signaling cascades and its effects are tissue- and cell type-specific. It often functions as an important regulator of cell-cell and cell-matrix interactions. |
| Clone | 1aG4/C5 |
| Immunogen | thymocytes from C3H/Di mice (Thy-1.2 positive) |
| Isotype | IgG3 |
| Specificity | The mouse monoclonal antibody 1aG4/C5 recognizes alloantigen Thy-1.2 of mouse Thy-1 (CD90); it does not cross-react with Thy-1.1 alloantigen. Thy-1 is an 18-35 kDa cell surface GPI linked glycoprotein (immunoglobulin superfamily); in mouse it is abundant on thymocytes and peripheral T lymphocytes. |
| Reactivity | Mouse |
| Applications | FA, FC, ICC, WB |
| Form | Azide free phosphate buffered saline (PBS), preserved by filter sterilization, approx. pH 7.4 |
| Storage | Store at 2-8°C. Do not freeze. |
| Supplier | Exbio |
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