| Product Name | Anti-CDC20 Antibody [rCDC20/7184] - BSA and Azide free |
|---|---|
| Description | Recombinant mouse monoclonal [rCDC20/7184] antibody to CDC20. |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | rCDC20/7184 |
| Conjugate | Unconjugated |
| Immunogen | Recombinant full lenth human CDC20 protein. |
| Isotype | IgG1 |
| Molecular Weight | 55 kDa |
| Target | CDC20 |
| Specificity | Cyclins, regulatory subunits, which associate with kinases, control many of the important steps in cell cycle progression. The Cdc2 protein kinase (p34Cdc2) exhibits protein kinase activity in vitro and exists in a complex with both cyclin B and a protein homologous to p13SUC1. Cdc2 kinase is the active subunit of the M phase promoting factor (MPF) and the M phase-specific Histone H1 kinase. The p34Cdc2/cyclin B complex is required for the G2 to M transition. An additional cell cycle-dependent protein kinase, termed p55cdc, exhibits a high degree of homology with the S. cerevisiae proteins Cdc20 and Cdc4. The p55cdc transcript is readily detectable in a variety of cultured cell lines in growth phase, but disappears when cell growth is chemically arrested. |
| Reactivity | Human |
| Applications | IHC-P |
| Working Dilutions | IHC-P: 1-2 µg/ml |
| Form | Liquid |
| Diluent Buffer | Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free. |
| Concentration | 1 mg/ml |
| Storage | Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. |
| Supplier | Antibodies.com |
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