Anti-Cdc20 (Cell Division Cycle Protein 20), Monoclonal Antibody
| Product Name | Anti-Cdc20 (Cell Division Cycle Protein 20), Monoclonal Antibody |
|---|---|
| Description | Cyclins, regulatory subunits, which associate with kinases, control many of the important steps in cell cycle progression. The Cdc2 protein kinase (p34Cdc2) exhibits protein kinase activity in vitro and exists in a complex with both cyclin B and a protein homologous to p13SUC1. Cdc2 kinase is the active subunit of the M phase promoting factor (MPF) and the M phase-specific Histone H1 kinase. The p34Cdc2/cyclin B complex is required for the G2 to M transition. An additional cell cycle-dependent protein kinase, termed p55cdc, exhibits a high degree of homology with the S. cerevisiae proteins Cdc20 and Cdc4. The p55cdc transcript is readily detectable in a variety of cultured cell lines in growth phase, but disappears when cell growth is chemically arrested. |
| Synonyms | CDC20, CDC20A, p55CDC, P55CDC-LSB |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | AR12 |
| Immunogen | Urea-denatured His6 Cdc20 human recombinant protein |
| Isotype | IgG1, kappa |
| Reactivity | Human |
| Applications | FC, IF, IHC |
| Form | 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml. |
| Gene Id | 991 |
| Uniprot | Q12834 |
| Storage | Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required. |
| References | Sironi L et al. 2001. EMBO J. 20(22):6371-82. |
| Supplier | ARP |
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