| Product Name | Anti-Cdk7 Activating Kinase (CAK) Monoclonal Antibody |
|---|---|
| Description | Human homolog is a subunit of trimeric cdk-activating kinase CAK, which inhibits RNA polymerase II transcription by reducing RNAPII and TFIIF entry into the preinitiation complex. Mouse Monoclonal Antibody to Cdk7 Activating Kinase (CAK). |
| Clonality | Monoclonal |
| Clone | Mo-1.1 |
| Immunogen | Recombinant C-terminal 221 aa fragment of human wild-type cdk7/CAK (cyclin activating kinase) |
| Isotype | IgG2b |
| Specificity | Mo-1.1 recognizes the key cell cycle regulator cdk7, which is essential to activate the cdk2 kinase in G1 phase and the cdc2 kinase in G2/M phase |
| Reactivity | Human, Mouse |
| Applications | FACS, IHC, WB |
| Form | Hybridoma culture supernatant |
| Storage | 2-8C |
| References | Tassan, J.P. et al. (1994) J. of Cell Biology 127 (2): 467-478 |
| Background | Human homolog is a subunit of trimeric cdk-activating kinase CAK, which inhibits RNA polymerase II transcription by reducing RNAPII and TFIIF entry into the preinitiation complex |
| Supplier | ARP |
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