| Product Name | Anti-C/EBP-Beta (clone 47A1) |
|---|---|
| Description | CCAAT/enhancer-binding proteins (C/EBPs) are a family of basic leucine zipper (bZIP) DNA binding proteins that play important roles in normal cellular differentiation and function in a variety of tissues. The C/EBP family is critical for innate immunity and inflammatory response, and consists of five core members: C/EBPalpha, C/EBPbeta, C/EBPdelta, C/EBPepsilon, and C/EBPgamma . Among these proteins, C/EBPbeta is usually highly expressed in liver, intestine, lung and adipose. C/EBPbeta has three isoforms, two activator, (LAP* and LAP) and a repressor (LIP). These isoforms are differentially translated from the same mRNA. The expression of these isoforms is developmentally and hormonally regulated. |
| Synonyms | CEBPB(CCAAT/enhancer binding protein, beta), LAP, CRP2, TCF5, IL6DBP, NF-IL6, MGC32080,C/EBP-beta, CCAAT/enhancer binding protein (C/EBP) beta, NFIL6, liver-enriched transcriptional activator protein, nuclear factor of interleukin 6, interleukin 6-dependent DNA-binding protein, |
| Host | Mouse |
| Clone | 47A1. Anti-human C/EBP beta mAb, clone 47A1, is derived from hybridization of mouse SP2/O myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human C/EBP beta protein. |
| Immunogen | Recombinant human C/EBP-beta (1-271 aa) purified from E. coli |
| Isotype | IgG1,K |
| Reactivity | Human, Mouse |
| Applications | ELISA, WB, Dot Blot |
| Form | Purified, in Phosphate-Buffered Saline (pH 7.4) with 0.1% Sodium Azide. |
| Storage | Can be stored at +4C. For long term storage, aliquot and store at -20C. Avoid repeated freezing and thawing cycles. |
| References | Lekstrom-Himes J. et al. (1998) J Biol. Chem. 273, 28545-28548 Parkin SE. et al. (2002) J Biol. Chem.; 277, 23563-23572 Su WC. et al. (2003) J Biol. Chem. 278, 51150-51158 |
| Supplier | ARP |
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