Anti-Clathrin Light Chain Antibody [SPM174] - BSA and Azide free
| Product Name | Anti-Clathrin Light Chain Antibody [SPM174] - BSA and Azide free |
|---|---|
| Description | Mouse monoclonal [SPM174] antibody to Clathrin Light Chain. |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | SPM174 |
| Conjugate | Unconjugated |
| Immunogen | Recombinant N terminal fragment of human Clathrin Light Chain. |
| Isotype | IgG2b |
| Molecular Weight | 31-44 kDa |
| Target | Clathrin Light Chain |
| Specificity | This antibody recognizes proteins of 31-44kDa, which are identified as Clathrin Light Chains (both A B). Clathrin is composed of three heavy chains and three light chains, which associate non-covalently to form a triskelion structure. Clathrin light chain regulates the self-assembly of triskelions onto intracellular membranes. Clathrin light chain subunits (LCA and LCB) contribute to regulation of coated vesicle formation to sort proteins during receptor-mediated endocytosis and organelle biogenesis. LCA and LCB are encoded by two discrete genes. They share only 60% homology, and have certain features in common. Both LCA and LCB undergo alternative mRNA splicing, which results in the generation of tissue-specific isoforms. |
| Reactivity | Human |
| Applications | FC, IF, IHC-P, WB |
| Working Dilutions | Flow Cytometry: 1-2 µg/million cells, IF: 1-2 µg/ml, WB: 1-2 µg/ml, IHC-P: 1-2 µg/ml |
| Form | Liquid |
| Diluent Buffer | Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free. |
| Concentration | 1 mg/ml |
| Storage | Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. |
| Supplier | Antibodies.com |
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