| Product Name | Anti-CLEC9A Antibody [8F9] |
|---|---|
| Description | Mouse monoclonal [8F9] antibody to CLEC9A. |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | 8F9 |
| Conjugate | Unconjugated |
| Immunogen | RBL-2H3 cells expressing human DNGR-1 fused to an HA epitope. |
| Isotype | IgG2a |
| Molecular Weight | 27 kDa |
| Target | CLEC9A |
| Specificity | This antibody recognizes a protein of 27kDa, identified as CLEC9A (C-type lectin domain family 9 member A). Its epitopes maps in aa 50-110. The C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily consists of a variety of proteins that share a common protein fold and have diverse functions, including cell-cell signaling, cell adhesion, glycoprotein turnover and immune responses. CLEC-9A, also known as DNGR1 (dendritic cell natural killer lectin group receptor 1), is a 241 amino acid single-pass type II membrane protein that contains one C-type lectin domain and belongs to the CTL/CTLD superfamily. Expressed in myeloid lineage cells, brain, spleen and thymus, CLEC-9A is a group V C-type lectin- like receptor (CTLR) that acts as an activation receptor. |
| Reactivity | Human |
| Applications | ELISA, FC, IF |
| Working Dilutions | Flow Cytometry: 1-2 µg/million cells, IF: 1-2 µg/ml |
| Form | Liquid |
| Diluent Buffer | Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide. |
| Concentration | 200 µg/ml |
| Storage | Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. |
| Supplier | Antibodies.com |
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