| Product Name | Anti-Clostridium difficile Toxin B Antibody [5156] |
|---|---|
| Description | Mouse monoclonal [5156] antibody to Clostridium difficile Toxin B. |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | 5156 |
| Conjugate | Unconjugated |
| Isotype | IgG1 |
| Target | Clostridium difficile Toxin B |
| Specificity | This antibody recognises Clostridium difficile toxin B. No reaction is observed with toxin A. Clostridium difficile is a gram-positive motile bacterium which is the leading cause of diarrhoea in developed countries. The incidence of disease in humans varies greatly with age, spore density and the administration of antibiotics. Toxin B (TcdB) is a large exotoxin. Its role in disease is less well understood than that of toxin A, though it seems clear that TcdB contributes to disease. Both toxins modify the Ras superfamily of small GTPases via glycosylation, inactivating them and leading to the disruption of vital signaling pathways in the cell. |
| Reactivity | Bacteria |
| Applications | ELISA |
| Working Dilutions | ELISA: 1:20 - 1:200 |
| Form | Liquid |
| Diluent Buffer | Supplied in Phosphate Buffered Saline with 0.1% Sodium Azide. |
| Concentration | 100 µg/ml |
| Storage | Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended. |
| Supplier | Antibodies.com |
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