| Product Name | Anti-Clostridium difficile Toxin A Antibody |
|---|---|
| Description | Rabbit polyclonal antibody to Clostridium difficile Toxin A. |
| Host | Rabbit |
| Clonality | Polyclonal |
| Conjugate | Unconjugated |
| Immunogen | Synthetic peptide sequence CTIDGKKYYFN corresponding to amino acids 2123 - 2132 of the native Clostridium difficile Toxin A conjugated to Keyhole Limpet Haemocyanin. |
| Isotype | IgG |
| Target | Clostridium difficile Toxin A |
| Amino Acid Sequence | CTIDGKKYYFN |
| Protein Length | 10 |
| Specificity | This antibody recognises Clostridium difficile toxin A. Clostridium difficile is a gram-positive motile bacterium and the leading cause of diarrhoea in developed countries. The incidence of disease in humans varies greatly with age, spore density, and the administration of antibiotics.Toxin A (TcdA) is a large exotoxin which is an essential virulence factor for C. difficile infection. TcdA has a molecular mass of ~308 kDa and is a glucosyltransferase, which irreversibly inactivates the Ras family of small GTPases to disrupt many important signalling pathways. |
| Reactivity | Bacteria |
| Applications | ELISA |
| Form | Liquid |
| Diluent Buffer | Supplied in Phosphate Buffered Saline with 0.09% Sodium Azide. |
| Concentration | 5 mg/ml |
| Storage | Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended. |
| Supplier | Antibodies.com |
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