Anti-CNDP2 (clone AT15E5)

Antibodies, Monoclonal Antibodies
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Product Name Anti-CNDP2 (clone AT15E5)
Description CNDP2, known as tissue carnosinase and peptidase A, is a nonspecific dipeptidase rather than a selective carnosinase and is a secreted peptidase homologous to M20 peptidases. Also known as glutamate carboxypeptidase-like protein 1(CPGL), CNDP2 is ubiquitously expressed throughout human tissue. CNDP2 Hydrolyzes a variety of dipeptides including L-carnosine but has a strong preference for Cys-Gly and may be play a role as tumor suppressor in hepatocellular carcinoma (HCC) cells.
Reactivity Human
Applications Dot blot, ELISA, WB
Clone AT15E5. Anti-human CNDP2 mAb, clone AT15E5, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human CNDP2 protein.
Concentration 0.1 mg/ml
Form Purified, in Phosphate-Buffered Saline (pH 7.4) with 0.1% Sodium Azide
Species Mouse
Host Mouse
Isotype IgG1, K
Immunogen Recombinant human CNDP2 (1-475aa) purified from E. coli
Interest Fields Metabolism
NCBI Number NP_060705
References Zhang, P., et al. (2006) Cancer res 12: 6617-6625Kaur, H., et al. (2009) J.Biol.Chem 284: 14493-14502Licker, V., et al. (2012) J proteomics 3;75(15): 4656-67
Storage Can be stored at +4C. For long term storage, aliquot and store at -20C. Avoid repeated freezing and thawing cycles.
Synonyms Cytosolic non-specific dipeptidase, CN2, CPGL, HsT2298, PEPA
Working Dilutions Optimal dilution should be performed by user.

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