| Product Name | Anti-CRLF2 (clone AT4E7) |
|---|---|
| Description | CRLF2 is cytokine receptor-like factor 2. Cytokine signals are mediated through specific receptor complexes, the components of which are mostly members of the type I cytokine receptor family. Type I cytokine receptors share conserved structural features in their extracellular domain. Receptor complexes are typically heterodimeric, consisting of alpha chains, which provide ligand specificity, and beta (or gamma) chains, which are required for the formation of high-affinity binding sites and signal transduction. |
| Synonyms | Cytokine receptor-like factor 2 isoform 1 precursor, CRL2, CRLF2Y, TSLPR |
| Host | Mouse |
| Clone | AT4E7. Anti-human CRLF2 mAb, clone AT4E7, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human CRLF2 protein. |
| Immunogen | Recombinant human CRLF2 (23-231aa) purified from E. coli |
| Isotype | K,IgG2a |
| Reactivity | Human, Mouse |
| Applications | ELISA, WB, Dot Blot |
| Form | Purified, in Phosphate-Buffered Saline (pH 7.4) containing 10% Glycerol, 0.02% Sodium Azide. |
| Storage | Can be stored at +4C. For long term storage, aliquot and store at -20C. Avoid repeated freezing and thawing cycles. |
| References | Blagoev B, Nielsen MM, Angrist M, et al. (2002). Gene 284 (1€“2): 161€“8.Reche PA, Soumelis V, Gorman DM, et al. (2001). J. Immunol. 167 (1): 336€“43. |
| Supplier | ARP |
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