| Product Name | Anti-CX3CL1 Antibody (Biotin) - BSA and Azide free |
|---|---|
| Description | Rabbit polyclonal antibody to CX3CL1 (Biotin). |
| Host | Rabbit |
| Clonality | Polyclonal |
| Conjugate | Biotin |
| Immunogen | Recombinant human fractalkine. |
| Isotype | IgG |
| Target | CX3CL1 |
| Specificity | This antibody recognises human fractalkine, otherwise known as CX3CL1, a 397 amino acid CX3C chemokine which signals through the CX3CR1 receptor and is expressed by various tissues including the brain, testis, lung, heart, kidney, colon and skeletal muscle.Adhesion of fractalkine to the CX3CR1 receptor triggers the chemotaxis and adhesion of leucocytes, including T cells, monocytes and NK cells and fractalkine is involved in the regulation of brain microglia during neuroinflammatory processes. CX3CL1 may also play a role in dendritic cell mediated host defense against invading pathogens such as Legionella pneumophila. |
| Reactivity | Human |
| Applications | ELISA, WB |
| Working Dilutions | ELISA: 0.15 - 0.30 µg/ml, WB: 0.1 - 0.2 µg/ml |
| Form | Lyophilized |
| Diluent Buffer | Supplied in Phosphate Buffered Saline. |
| Concentration | 100 µg/ml after reconstituiton. |
| Storage | Lyophilized: Store at -20°C. Reconstituted: Store undiluted at -20°C, avoid freeze / thaw cycles. Storage in frost free freezers is not recommended. Should this product contain a precipitate we recommend microcentrifugation before use. |
| Supplier | Antibodies.com |
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