| Product Name | Anti-CXCL9 Antibody [C09-9H7] (Biotin) |
|---|---|
| Description | Mouse monoclonal [C09-9H7] antibody to CXCL9 (Biotin). |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | C09-9H7 |
| Conjugate | Biotin |
| Immunogen | E. coli derived recombinant human full length CXCL9 (Thr23-Thr125). |
| Isotype | IgG1 |
| Target | CXCL9 |
| Specificity | This antibody recognises C-X-C motif chemokine 9 (CXCL9), also known as Monokine induced by Interferon-Gamma (MIG) and small inducible cytokine B9. Synthesis of CXCL9 is induced by IFN-gamma and it mediates lymphoytic infiltration to focal sites and inhibits tumor growth. CXCL9 is not detectable under physiological conditions in non-lymphoid tissues. However in response to inflammation or injury, IFN-gamma induces CXCL9 production in blood and tissue cells. CXCL9 is a ligand of CXCR3, a classic 7 transmembrane G protein coupled receptor. Upon binding to this receptor the signaling pathways Src, PI3k and MAPK can be activated. The biotinylated Mouse anti Human CXCL9 antibody, clone C09-9H7 (MCA6253B) can be used as a detection antibody in a sandwich ELISA with the purified Mouse anti Human CXCL9 antibody, clone C04-3E4 (MCA6252GA) as the capture antibody. |
| Reactivity | Human |
| Applications | ELISA |
| Working Dilutions | ELISA: 1 µg/ml |
| Form | Liquid |
| Diluent Buffer | Supplied in Phosphate Buffered Saline with 1% BSA and 0.09% Sodium Azide. |
| Concentration | 100 µg/ml |
| Storage | Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended. This product is photosensitive and should be protected from light. |
| Supplier | Antibodies.com |
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