| Product Name | Anti-CXCR4 Antibody |
|---|---|
| Description | Goat polyclonal antibody to CXCR4. |
| Host | Goat |
| Clonality | Polyclonal |
| Conjugate | Unconjugated |
| Immunogen | Synthetic peptide sequence TEEMGSGDYDSMKEPCFREENANFNKC corresponding to amino acids 17-43 within the N-terminus of human CD184 / CXCR4. |
| Isotype | IgG |
| Target | CXCR4 |
| Amino Acid Sequence | TEEMGSGDYDSMKEPCFREENANFNKC |
| Protein Length | 27 |
| Specificity | This antibody recognises an epitope within the N-terminal region of human CD184, otherwise known as CXCR4 (C-X-C chemokine receptor type 4), a transmembrane glycoprotein and member of the G-protein coupled receptor 1 family, ubiquitously expressed in blood and tissue cells, which acts as a specific receptor for the chemokine SDF-1 (Stromal cell-derived factor 1). Interaction of CD184 with SDF-1 mediates the chemotaxis of progenitor and mature blood cells, and is critical for B- lymphopoiesis and myelopoiesis. CD184 is a major co-receptor for infection by T-cell tropic strains of HIV1, and also a primary receptor for some HIV2 isolates. Goat anti Human CD184 / CXCR4 antibody is being suitable for use in immunofluorescence. |
| Reactivity | Human, Rat |
| Applications | ELISA, IHC-P, WB |
| Working Dilutions | ELISA: 1:25,000, IHC-P: 1:150, WB: 1:250 |
| Form | Liquid |
| Diluent Buffer | Supplied in Phosphate Buffered Saline with 0.1% BSA and 0.1% Sodium Azide. |
| Concentration | 1 mg/ml |
| Storage | Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended. |
| Supplier | Antibodies.com |
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