| Product Name | Anti-CXCR5 Antibody [CXCR5/8279R] - BSA and Azide free |
|---|---|
| Description | Recombinant rabbit monoclonal [CXCR5/8279R] antibody to CXCR5. |
| Host | Rabbit |
| Clonality | Monoclonal |
| Clone | CXCR5/8279R |
| Conjugate | Unconjugated |
| Immunogen | Recombinant fragment (around Amino Acids 1-200) of human CXCR5 protein. The exact sequence is proprietary. |
| Isotype | IgG |
| Molecular Weight | 56 kDa |
| Target | CXCR5 |
| Specificity | Burkitt s lymphoma receptor 1 (Blr1) is a lymphocyte specific chemokine receptor expressed at low levels in secondary lymphoid tissues and in defined structures of the cerebellum. The G protein-coupled receptor has significant homology to other chemokine receptors. Stimulation of Blr1 by its ligand, B-lymphocyte chemoattractant (BLC) results in an influx of calcium into the cell and the chemotaxis of the cell. Blr1 is required for B-cell migration into splenic and Peyer s patch follicles. BLC expression in Peyer s patches is highest in germinal centers, where B cells undergo somatic mutation and affinity maturation. |
| Reactivity | Human |
| Applications | IHC-P |
| Working Dilutions | IHC: 1-2 µg/ml |
| Form | Liquid |
| Diluent Buffer | Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free. |
| Concentration | 1 mg/ml |
| Storage | Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. |
| Supplier | Antibodies.com |
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